Leaving from Buenos Aires along route 7 to Luján on the west access, and then taking national route 5 passing by Mercedes, Chivilcoy, Bragado, 9 de Julio, C.Casares, Pehuajó, Trenque Lauquen, Pellegrini and Catriló, after 607 km. you arrive at Santa Rosa.
From the south, passing by Neuquén you have three options: the route of the dessert, national route 151 (Catriel - 25 de mayo - Chacharramendi) 537 km.
Along national route 22 (Gral. Roca - Chelforó - Gdor. Duval - Parque Nac. Lihuel Calel) 538 km. or a new and shorter road along provincial route 6 (Gral. Roca - Dique Casa de Piedra - Parque Nac. Lihuel Calel) 526 km.
Along all of them until the junction with national route 35 (Cruce Padre Buodo) direct to Santa Rosa.
From the north and the west joining national route 35.
From the northwest, national route 33 until the juncture with national route 35.
Distances from Santa Rosa to:
Aluminé 848 km
Bahia Blanca 327 km
Buenos Aires 607 km
Comodoro Rivadavia 1286 km
25 de mayo 409 km
Neuquén 526 km
Cutral Có 631 km
Junin de los Andes via Zapala (R 22 y 40) 908 km, via Piedra del Aguila (237 y 40) 911 km
Paso Icalma 848 km
Paso Mamuil Malal 985 km
Paso Pino Hachado 845 km
Piedra del Aguila 752 km
Plaza Huincul 631 km
Puerto Montt 1281 km
Pucón 889 km
Rawson 857 km
Rio Gallegos 2231 km 1412 km
San Carlos de Bariloche via 7 Lagos (R 234 y 231) 1134 km via Confluencia (R 237) 955 km
San Martín de los Andes (Por Zapala) 949 km
Temuco (via Icalma) 994 km
Temuco (viaPino Hachado) 1060 km
Temuco (viaMamuil Malal ) 1173 km
Villa La Angostura 1058 km
Villa Pehuenia 898 km
Villa Traful (por 7 lagos) 1058 km
Villarrica 903 km
Ushuaia 2618 km
Viedma 602 km
Monte Hermoso 435 km