From Buenos Aires, leaving to the south along national route 3 passing by Cañuelas, Tres Arroyos, and Cnel Dorrego you get to Bahia Blanca, then take national route 3 and continue to Carmen de Patagones and Viedma.
From Neuquén along national route 22 you travel through the High and the Low Valley of the Rio Negro until Médanos and there you turn to the east along national route 3 to Viedma.
Distances from Viedma to:
Bahia Blanca 275 km
Buenos Aires 963 km
Bariloche 845 km
Comodoro Rivadavia 894 km
El Calafate 1785 km
Esquel 1109 km
Neuquén 564 km
Puerto Madryn 447 km
Rawson 528 km
Rio Gallegos 1682 km
Rio Grande 2028 km
Santa Cruz 1520 km
Santa Rosa 607 km
Trelew 509 km
Ushuaia 2622 km